B-NGF Beta-Nerve Growth Factor Mouse protein

• Description:

  NGF beta Mouse produced in Submaxillary Gland of Grown Mouse is a homodimer, non-glycosylated, polypeptide chain containing 2 identical 120 amino acids and having a molecular mass of 13,471 Dalton each. The NGF beta Mouse is purified by advanced biology purification technology.

• Synonyms:

  Beta Polypeptide; NGF; NGFB; HSAN5; Beta-NGF; MGC161426; MGC161428

• Gene Name:

  NGF

• UniProt:

  P01139

• Reactivity:

  Mouse

• Source:

  Submaxillary gland of grown mouse

• Sequence:

  [object Object]

• Purification:

  Greater than 98% as determined by (a) Analysis by RP-HPLC and (b) Analysis by SDS-PAGE .

• Bioactivity:

  The method used to test the bioassay is the NGF-dependent survival of dorsal root ganglia neurons of chick embryo, corresponding to a Specific Activity of 500,000IU/mg.

• Form:

  Sterile Filtered White lyophilized (freeze-dried) powder.

• Reconstitution:

  It is recommended to reconstitute the lyophilized Murine NGF-beta in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

• Function:

  Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI.

• Shipping Conditions:

  Available

• Storage Conditions:

  Lyophilized Mouse Beta-NGF although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Murine NGF-Beta should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles.

• Other Gene Names:

  Beta-nerve growth factor

• Subcellular Location:

  Secreted.