Fractalkine Rat Recombinant Protein (CX3CL1)

• Description:

  Fractalkine Rat Recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain containing 76 amino acids and having a molecular mass of 8.7kDa. The Fractalkine is purified by proprietary chromatographic techniques.

• Synonyms:

  Fractalkine; CX3CL1; Neurotactin; CX3C membrane-anchored chemokine; Small inducible cytokine D1; NTN; NTT; CXC3; CXC3C; SCYD1; ABCD-3; C3Xkine

• Gene Name:

  CX3CL1

• UniProt:

  O55145

• Reactivity:

  Rat

• Tissue Specificity:

  Highest levels in brain (neurons) . Significant levels in kidney, heart, lung and adrenal gland.

• Source:

  Escherichia coli

• Sequence:

  [object Object]

• Purification:

  Greater than 97.0% as determined by SDS-PAGE.

• Bioactivity:

  Determined by its ability to chemoattract human monocytes using a concentration range of 5.0-10.0 ng/ml, corresponding to a specific activity of 100,000-200,000units/mg.

• Form:

  Sterile Filtered White lyophilized (freeze-dried) powder.

• Reconstitution:

  2

• Function:

  The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1.

• Shipping Conditions:

  Available

• Storage Conditions:

  Lyophilized FractalkineRat although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Fractalkine should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles.

• Other Gene Names:

  Fractalkine

• Subcellular Location:

  Cell membrane