Fractalkine Mouse Recombinant Protein (CX3CL1)

• Description:

  Fractalkine Mouse Recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain containing 76 amino acids and having a molecular mass of 8.7kDa. The CX3CL1 is purified by proprietary chromatographic techniques.

• Synonyms:

  Fractalkine; C-X3-C motif chemokine 1; CX3C membrane-anchored chemokine; Neurotactin; Small-inducible cytokine D1; Cx3cl1; Cx3c; Fkn; Scyd1; CX3C; ABCD-3; AB030188; AI848747; D8Bwg0439e

• Gene Name:

  CX3CL1

• UniProt:

  O35188

• Reactivity:

  Mouse

• Tissue Specificity:

  Highest levels in brain. Lower levels in kidney, heart and lung. Also found in skeletal muscle and testis.

• Source:

  Escherichia coli

• Sequence:

  [object Object]

• Purification:

  Greater than 97.0% as determined by (a) Analysis by RP-HPLC and (b) Analysis by SDS-PAGE.

• Bioactivity:

  50

• Form:

  Sterile Filtered White lyophilized (freeze-dried) powder.

• Reconstitution:

  It is recommended to reconstitute the lyophilized CX3CL1 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

• Function:

  The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium (By similarity) . Binds to CX3CR1.

• Shipping Conditions:

  Available

• Storage Conditions:

  Lyophilized CX3CL1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CX3CL1 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Please prevent freeze-thaw cycles.

• Other Gene Names:

  Fractalkine

• Subcellular Location:

  Cell membrane; Single-pass type I membrane protein.