CTF1 Cardiotrophin-1 Rat Recombinant Protein

• Description:

  Cardiotrophin-1 Rat Recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain containing 203 amino acids and having a molecular mass of 21.4kDa. The CTF1 Rat is purified by proprietary chromatographic techniques.

• Synonyms:

  Cardiotrophin-1; CT-1; Ctf1

• Gene Name:

  CTF1

• UniProt:

  Q63086

• Reactivity:

  Rat

• Tissue Specificity:

  Expressed in the ventricle and atrium of adult rats. Also detected in the lung, kidney, liver, skeletal muscle, stomach and urinary bladder. Not detected in brain, colon, testis, spleen or thymus. Overexpressed in the ventricles in the case of hypertension and hypertrophy.

• Source:

  Escherichia coli

• Sequence:

  [object Object]

• Purification:

  Greater than 95.0% as determined by SDS-PAGE and HPLC analyses.

• Bioactivity:

  506

• Form:

  Sterile Filtered White lyophilized (freeze-dried) powder.

• Reconstitution:

  It is recommended to reconstitute the lyophilized CTF1 in sterile 4mM HCl not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

• Function:

  Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.

• Shipping Conditions:

  Available

• Storage Conditions:

  Lyophilized Cardiotrophin-1 Rat although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CTF1 Rat should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.

• Other Gene Names:

  Cardiotrophin-1

• Subcellular Location:

  Secreted