CTF1 Cardiotrophin-1 Mouse Recombinant Protein

• Description:

  CTF1 Mouse Recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain containing 202 amino acids and having a molecular mass of 21.3kDa. The CTF1 Mouse is purified by proprietary chromatographic techniques.

• Synonyms:

  CTF1; CT1; CT-1; Cardiophin 1

• Gene Name:

  CTF1

• UniProt:

  Q60753

• Reactivity:

  Mouse

• Tissue Specificity:

  Highly expressed in heart, skeletal muscle, liver, lung and kidney. Lower levels in testis and brain. No expression in spleen.

• Source:

  Escherichia coli

• Sequence:

  [object Object]

• Purification:

  Greater than 98.0% as determined by SDS-PAGE.

• Bioactivity:

  The ED50 as determined by the dose-dependent proliferation of TF-1 cells was less than 1.0ng/ml, corresponding to a specific activity of greater than 1,000,000units/mg.

• Form:

  Sterile Filtered White lyophilized (freeze-dried) powder.

• Reconstitution:

  Reconstitute the lyophilized CTF1 in sterile 4mM HCl to a concentration of 0.1-0.5 mg/ml. Stock solutions should be apportioned into working aliquots and stored at <-20°C. Further dilutions should be made in appropriate buffered solutions.

• Function:

  Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.

• Shipping Conditions:

  Available

• Storage Conditions:

  Lyophilized CTF1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CTF1 should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.

• Other Gene Names:

  Cardiotrophin-1

• Subcellular Location:

  Secreted.