IL-4 Interleukin-4 Rhesus Macaque Recombinant Protein

• Description:

  IL-4 Rhesus Macaque Recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain containing 129 amino acids and having a molecular mass of 14.9kDa. The IL4 Rhesus Macaque is purified by proprietary chromatographic techniques.

• Synonyms:

  Interleukin-4; IL-4; B-cell stimulatory factor 1; BSF-1; Lymphocyte stimulatory factor 1; IL4

• Gene Name:

  IL4

• UniProt:

  P51492

• Reactivity:

  Monkey

• Source:

  Escherichia coli

• Sequence:

  [object Object]

• Purification:

  Greater than 97.0% as determined by (a) Analysis by RP-HPLC and (b) Analysis by SDS-PAGE.

• Bioactivity:

  506

• Form:

  Sterile Filtered White lyophilized (freeze-dried) powder.

• Reconstitution:

  It is recommended to reconstitute the lyophilized Interleikin-4 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

• Function:

  Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages.

• Shipping Conditions:

  Available

• Storage Conditions:

  Lyophilized Interleukin-4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL4 should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles.

• Other Gene Names:

  Interleukin-4

• Subcellular Location:

  Secreted.