Anti-Calcipressin 1 Rabbit Monoclonal Antibody, Carrier-free

• Description:

  Boster Bio Anti-Calcipressin 1 Rabbit Monoclonal Antibody catalog # M02795-1. Tested in WB application. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Histone-lysine N-methyltransferase SETD7;2.1.1.43;Histone H3-K4 methyltransferase SETD7;H3-K4-HMTase SETD7;Lysine N-methyltransferase 7;SET domain-containing protein 7;SET7/9;SETD7;KIAA1717, KMT7, SET7, SET9;

• Gene Name:

  Histone-lysine N-methyltransferase SETD7

• UniProt:

  P53805

• Host:

  Rabbit

• Reactivity:

  Human,Mouse,Rat

• Immunogen:

  A synthesized peptide derived from human Calcipressin 1

• Clonality:

  Monoclonal

• Clone:

  Clone: 28R02

• Tissue Specificity:

  Widely expressed. Expressed in pancreatic islets.

• Applications:

  WB

• Purification:

  Affinity-chromatography

• Concentration:

  Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

• Form:

  Liquid

• Reconstitution:

  Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

• Function:

  Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation. .

• Components:

  Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

• Storage Conditions:

  Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  40721 MW

• Observed Molecular Weight:

  28 kDa

• Fragment:

  IgG

• Applications Notes:

  WB 1:500-1:2000

• Subcellular Location:

  Nucleus. Chromosome .

• Protein Name:

  T-cell surface glycoprotein CD3 zeta chain