Anti-Phospho-c-Jun (S63) Rabbit Monoclonal Antibody, Carrier-free

• Description:

  Boster Bio Anti-Phospho-c-Jun (S63) Rabbit Monoclonal Antibody catalog # P02038. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

• Phospho Site:

  S63

• Synonyms:

  Transcription factor AP-1;Activator protein 1;AP1;Proto-oncogene c-Jun;V-jun avian sarcoma virus 17 oncogene homolog;p39;JUN;

• Gene Name:

  Transcription factor AP-1

• UniProt:

  P05412

• Host:

  Rabbit

• Reactivity:

  Human,Mouse,Rat

• Immunogen:

  A synthesized peptide derived from human Phospho-c-Jun (S63)

• Clonality:

  Monoclonal

• Clone:

  Clone: IGA-10

• Tissue Specificity:

  Expressed in brain, and to a lesser extent in lung, kidney and testis.

• Applications:

  WB,IHC,ICC,IF

• Purification:

  Affinity-chromatography

• Concentration:

  Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

• Form:

  Liquid

• Function:

  Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306). .

• Components:

  Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

• Storage Conditions:

  Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  35676 MW

• Observed Molecular Weight:

  43 kDa

• Fragment:

  Rabbit IgG

• Applications Notes:

  WB 1:500-1:2000
  IHC 1:50-1:200
  ICC/IF 1:50-1:200

• Subcellular Location:

  Nucleus.