Anti-c-Jun (phospho-S243) Antibody

• Description:

  Boster Bio Anti-c-Jun (phospho-S243) Antibody catalog # A02038S243. Tested in IHC, IP applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Transcription factor AP-1; Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39; JUN;

• Gene Name:

  JUN

• UniProt:

  P05412

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic phosphopeptide derived from human c-Jun around the phosphorylation site of Serine 243.

• Clonality:

  Polyclonal

• Applications:

  IHC, IP

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Form:

  Liquid

• Function:

  Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306) . Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306) .

• Molecular Weight:

  35676 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Transcription factor AP-1

• Subcellular Location:

  Nucleus.

• Protein Name:

  Transcription factor AP-1