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MCRAMP, mouse

CAT: 0013-GTR19066503-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19066503-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MCRAMP (mouse) or mouse calethicidin-related antimicrobial peptide, is the sole murine cathelicidin and intestinal homologue of human LL-37. mCRAMP expression in the intestinal tract is restricted to surface epithelial cells in the colon where it exhibits antimicrobial activity against enteric pathogens and it is established as a component of the innate antimicrobial defense in mice. mCRAMP deficiency has been linked to alcoholic liver disease (ALD) in mice and it also produces viral-induced responses in mouse cells. mCRAMP synergises wirh rifamycin for intracellular killing of mycobacteria.
Purity
≥95%
Molecular Weight
3878.7
Notes
For research use only.
AA Sequence
GLLRKGGEKIGEKLKKIGQKIKNFFQKLVPQPEQ

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