5-Methoxyuridine

• UNSPSC Description:

  5-Methoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/5-methoxyuridine.html

• Purity:

  99.98

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)|H2O : 35 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(NC(C(OC)=C2)=O)=O)O1

• Molecular Weight:

  274.23

• References & Citations:

  [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  35542-01-9