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LP44 (hydrochloride)

CAT: 0804-HY-103101-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-103101-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LP44 (hydrochloride) is a selective 5-HT7 agonist with Ki of 0.22 nM. LP44 (hydrochloride) induces hypothermic effect in a dose-dependent manner by intracerebroventricular injection. LP44 (hydrochloride) not causes considerable hypothermic response by intraperitoneal administration[1].
CAS Number
824958-12-5
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/lp44-hydrochloride.html
Purity
98.12
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(CCCCCN1CCN(C(C=CC=C2)=C2SC)CC1)NC3C4=CC=CC=C4CCC3.Cl
Molecular Formula
C27H38ClN3OS
Molecular Weight
488.13
References & Citations
[1]Naumenko VS, et al. On the role of brain 5-HT7 receptor in the mechanism of hypothermia: comparison with hypothermia mediated via 5-HT1A and 5-HT3 receptor. Neuropharmacology. 2011 Dec;61 (8) :1360-5.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT7 Receptor

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