Rat CD3 epsilon&CD3 delta Heterodimer Protein, Llama Fc Tag&Llama Fc Tag (MALS verified)

• Background:

  T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.

• Description:

  Rat CD3E&CD3D Heterodimer Protein, Llama Fc Tag&Llama Fc Tag (CDD-R5257) is expressed from human 293 cells (HEK293). It contains AA Gln 21 - Asp 103 (CD3E) & Phe 22 - Gly 106 (CD3D) (Accession # D4A5M2-1 (CD3E) & P19377-1 (CD3D)).

• Specifications:

  Rat CD3E&CD3D Heterodimer Protein, Llama Fc Tag&Llama Fc Tag is produced by co-expression of CD3E and CD3D, has a calculated MW of 40.8 kDa (CD3E) and 40.9 kDa (CD3D). Subunit CD3E is fused with a llama IgG2b Fc tag at the C-terminus and subunit CD3D is fused with a llama IgG2b Fc tag at the C-terminus. The reducing (R) protein migrates as 55-60 kDa due to glycosylation.

• Expression Region:

  Gln 21 - Asp 103 (CD3E) & Phe 22 - Gly 106 (CD3D)

• Host:

  HEK 293

• Target:

  CD3E & CD3D

• Conjugation:

  Unconjugated

• Tag:

  C-LlamaFc(LlamaIgG2b) | C-LlamaFc(LlamaIgG2b)

• Source:

  Rat

• Stability:

  -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.

• Endotoxin:

  1.0 EU per μg

• Purity:

  95%

• Format:

  Powder

• Buffer:

  PBS, pH7.4

• Additives:

  Trehalose

• Molecular Weight:

  40.8 kDa (CD3E) & 40.9 kDa (CD3D)

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C