PE-Labeled Human HLA-A*11:01&B2M Tetramer Protein (Peptide free)

PE-Labeled Human HLA-A*11:01&B2M Tetramer Protein (Peptide free)

• Background: Human papillomavirus (HPV) is A kind of papillomavirus belonging to the milk polypoid virus family. It is a spherical DNA virus, which can cause the proliferation of squamous epithelium of human skin mucosa. HPV(human papillomavirus) for common warts, genital warts (condyloma acuminatum), and other symptoms. There are many types of human papillomavirus (HPV), with HPV 16 and 18 being high-risk types known to significantly increase the risk of cervical, vaginal and vulvar cancers in women and men. The PE-labeled human HLA-A*1101 HPV (IVCPICSQK) tetramer protein is a complex of HLA-A*1101 of the MHC Class I, B2M, and IVCPICSQK peptide of the HPV.
• Description: PE-Labeled Human HLA-A*11:01&B2M Tetramer Protein (HLM-HP2H5) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Thr 305 (HLA-A*11:01) & Ile 21 - Met 119 (B2M) (Accession # Q5S3G3-1 (HLA-A*11:01) & P61769 (B2M)).
• Specifications: PE-Labeled Human HLA-A*11:01&B2M Tetramer Protein is assembled by biotinylated monomer (HLM-H82W5) and PE-labeled streptavidin. Biotinylated Human HLA-A*11:01&B2M Monomer Protein is produced by co-expression of HLA and B2M. This Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).
• Expression Region: Gly 25 - Thr 305 (HLA-A*11:01) & Ile 21 - Met 119 (B2M)
• Host: HEK 293
• Target: HLA-A*1101 & B2M
• Conjugation: PE Labeled
• Tag: C-10×His
• Source: Human
• Stability: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Endotoxin: 1.0 EU per μg
• Bioactivity: Immobilized PE-Labeled Human HLA-A*11:01&B2M Tetramer Protein (Cat. No. HLM-HP2H5) at 1 μg/mL (100 μL/well) can bind Anti-HLA class I Antibody, Human IgG1 (W6/32) with a linear range of 0.06-4 ng/mL (QC tested).
• Format: Powder
• Buffer: PBS, 1% BSA, pH7.4
• Additives: Trehalose
• Molecular Weight: 36.0 kDa and 11.7 kDa
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, aviod light