Anti-SDHAF2 Antibody

CAT: 0519-A07635Size: 0.1 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0519-A07635Size:0.1 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Background

SDHAF2 (Succinate dehydrogenase complex assembly factor 2) encodes a mitochondrial protein needed for FAD cofactor attach to the SDH enzyme which plays a critical role in mitochondria. SDHAF2 is a tumor suppressor, but recent evidence suggests that somatic mutations of the SDHAF2 are unlikely to contribute to parathyroid tumor development in sporadic primary hyperparathyroidism.

Description

Boster Bio Anti-SDHAF2 Antibody (Catalog # A07635) . Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Synonyms

PGL2, SDH5, C11orf79, PGL2, Succinate dehydrogenase assembly factor 2, mitochondrial, Succinate dehydrogenase subunit 5, SDH assembly factor 2

Gene Name

SDHAF2

UniProt

Q9NX18

Host

Chicken

Reactivity

Human, Mouse, Rat

Cross Reactivity

SDHAF2 antibody is predicted to not cross-react with other SDHAF protein family members.

Immunogen

SDHAF2 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human SDHAF2. The immunogen is located within the first 50 amino acids of SDHAF2.

Clonality

Polyclonal

Applications

ELISA, WB

Field of Research

Cancer, Cell Cycle

Purification

SDHAF2 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.

Molecular Weight

19599 MW

Shipping Conditions

Available

Storage Conditions

SDHAF2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgY

Other Gene Names

Succinate dehydrogenase complex

Subcellular Location

Mitochondrion matrix

Prediction Reactivity

Bovine

Protein Name

Succinate dehydrogenase complex

UniProtKB · Q9NX18

Succinate dehydrogenase assembly factor 2, mitochondrial

SDHF2_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q9NX18
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: SDHAF2
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: SDH assembly factor 2, SDHAF2
EC number: —
Processing: Precursor
Secondary accessions: —

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

Chaperone

Disease

Disease variant

Cellular component

Mitochondrion

Domain

Transit peptide

Related Products

Catalog	Name
A07635-1	Anti-SDH5/SDHAF2 Antibody
PROTQ9NX18-100ug	Human SDHAF2 Recombinant Protein
PROTQ9NX18-01	Human SDHAF2 Recombinant Protein
PROTQ9NX18-500ug	Human SDHAF2 Recombinant Protein
PROTQ9NX18-20ug	Human SDHAF2 Recombinant Protein
LS054949-100ug	SDHAF2 (NM_017841) Human Over-expression Lysate
LS054949-20ug	SDHAF2 (NM_017841) Human Over-expression Lysate
LS054949	SDHAF2 (NM_017841) Human Over-expression Lysate
A11628	Anti-SDHAF1 Antibody
A01753-1	Anti-SDHA Antibody

Alternative Products

Catalog	Name
CQA5839-01	Anti-SDHAF2 Antibody
GTR17896855-01	SDHAF2 Antibody
MBS8570879-01	SDHAF2 Polyclonal Antibody
GTR17916370-01	SDHAF2 Antibody (Biotin)
pro-593	SDHAF2
GTR17916367-01	SDHAF2 Antibody (HRP)