Anti-SH3 domain-binding protein 4 SH3BP4 Antibody

Anti-SH3 domain-binding protein 4 SH3BP4 Antibody

• Background: SH3BP4 was initially isolated as a novel cDNA using differential display analysis using cultured human corneal fibroblasts. The protein contains three Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. SH3BP4 has been shown to interact with specific endocytic proteins such as clathrin, dynamin, and the transferrin receptor (TfR) and localizes to TfR-containing coated pits and vesicles. It is thought to be involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of TfR. At least two isoforms of SH3BP4 are known to exist.
• Description: Boster Bio Anti-SH3 domain-binding protein 4 SH3BP4 Antibody (Catalog # A09036). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.
• Synonyms: TTP, BOG25, EHB10, TTP, SH3 domain-binding protein 4, EH-binding protein 10
• CAS Number: 9007-83-4
• Gene Name: SH3BP4
• UniProt: Q9P0V3
• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Immunogen: SH3BP4 antibody was raised against an 18 amino acid synthetic peptide from near the carboxy terminus of human SH3BP4. The immunogen is located within amino acids 860 - 910 of SH3BP4.
• Clonality: Polyclonal
• Applications: ELISA, WB, IHC-P
• Purification: SH3BP4 Antibody is affinity chromatography purified via peptide column.
• Concentration: 1 mg/mL
• Form: Liquid
• Molecular Weight: 107496 MW
• Components: SH3BP4 Antibody is supplied in PBS containing 0.02% sodium azide.
• Storage Conditions: SH3BP4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Fragment: IgG