Anti-Histone H2B (mono methyl K116) Rabbit Monoclonal Antibody

• Description:

  Boster Bio Anti-Histone H2B (mono methyl K116) Rabbit Monoclonal Antibody catalog # M07286-3. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Histone H2B type 2-E; Histone H2B-GL105; Histone H2B.q; H2B/q; HIST2H2BE; H2BFQ

• Gene Name:

  Histone H2B type 2-E

• UniProt:

  Q16778

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthesized peptide derived from human Histone H2B (mono methyl K116)

• Clonality:

  Monoclonal

• Clone:

  Clone: 27H07

• Tissue Specificity:

  Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells.

• Applications:

  WB, IHC, ICC, IF

• Field of Research:

  2339, Epigenetics and Nuclear Signaling, Histones, Unmodified

• Purification:

  Affinity-chromatography

• Concentration:

  Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

• Form:

  Liquid

• Reconstitution:

  Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

• Function:

  Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment:

  IgG

• Applications Notes:

  WB 1:500-1:2000
  IHC 1:50-1:200
  ICC/IF 1:50-1:200

• Other Gene Names:

  HIST2H2BE

• Subcellular Location:

  Nucleus. Chromosome.

• Protein Name:

  T-cell surface glycoprotein CD3 zeta chain