Ribonuclease T2 from Aspergillus oryzae, Recombinant

Ribonuclease T2 from Aspergillus oryzae, Recombinant

• Description: Aspergillus oryzae Ribonuclease T2 is a member of the RNase T2 family of endonucleases that are present in a wide variety of microbial, plant and animal species. In contrast to Aspergillus oryzae Ribonuclease T1, which is an exclusively guanylic-acid specific endonuclease, all RNase T2-like enzymes are essentially base non-specific. However, RNase T2 endonucleases from different species can show slight base preferences. The fungal enzymes, including Aspargillus oryzae RNaseT2, show slight base preference in the following order: A>G>C, U. RNase T2 cleaves between the 3’-phosphate residue of one base and the 5’-OH residue of the adjacent nucleotide forming a 2’, 3’-cyclic phosphate intermediate followed by the generation of oligonucleotides with 3’-phosphate residues. This enzyme is also used as a non- mammalian source of RNase in various applications.
• CAS Number: 9000-83-3
• Activity: >10,000 U/mg protein
• Storage Conditions: Store at 2-8°C