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Solasodine

CAT: 0804-HY-N0068-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0068-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Solasodine (Purapuridine) is a steroidal alkaloid that occurs in plants of the Solanaceae family. Solasodine has neuroprotective, antifungal, hypotensive, anticancer, antiatherosclerotic, antiandrogenic and anti-inflammatory activities[1][2].
CAS Number
126-17-0
Product Name Alternative
Purapuridine; Solancarpidine; Solasodin
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; E1/E2/E3 Enzyme; Fungal; MDM-2/p53
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Solasodine.html
Purity
99.81
Solubility
DMSO : 1.96 mg/mL (ultrasonic; warming; adjust pH to 5 with HCl; heat to 60°C) |Ethanol : 20 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL
Smiles
C[C@H](CC1)CN[C@]21O[C@@]3([H])C[C@@]4([H])[C@]5([H])CC=C6C[C@@H](O)CC[C@]6(C)[C@@]5([H])CC[C@]4(C)[C@@]3([H])[C@@H]2C
Molecular Formula
C27H43NO2
Molecular Weight
413.64
Precautions
H302, H315, H319, H335
References & Citations
[1]Lecanu L, et al. The naturally occurring steroid solasodine induces neurogenesis in vitro and in vivo. Neuroscience. 2011 Jun 2;183:251-64.|[2]Chauhan K, et al. Anticonvulsant activity of solasodine isolated from Solanum sisymbriifolium fruits in rodents. Pharm Biol. 2011 Feb;49 (2) :194-9.|[3]Akhtar S, et al. Evaluation and Elucidation Studies of Natural Aglycones for Anticancer Potential using Apoptosis-Related Markers: An In silico Study. Interdiscip Sci. 2018 Jun;10 (2) :297-310.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
Phase 2

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