5'-ODMT cEt N-Bz A Phosphoramidite (Amidite)

5'-ODMT cEt N-Bz A Phosphoramidite (Amidite)

• CAS Number: 1197033-19-4
• UNSPSC Description: 5'-ODMT cEt N-Bz A Phosphoramidite Amidite is a locked nucleic acid (LNA) analogue. 5'-ODMT cEt N-Bz A Phosphoramidite Amidite possesses hybridization and mismatch discrimination attributes similar to those of LNA and shows resistance to exonuclease digestion[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/5-odmt-cet-n-bz-a-phosphoramidite-amidite.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: COC(C=C1)=CC=C1C(C2=CC=C(C=C2)OC)(C3=CC=CC=C3)OC[C@]45[C@H]([C@](O[C@H]5C)([H])[C@H](N6C7=NC=NC(NC(C8=CC=CC=C8)=O)=C7N=C6)O4)OP(OCCC#N)N(C(C)C)C(C)C
• Molecular Weight: 899.97
• References & Citations: [1]Seth PP, et al. Synthesis and biophysical evaluation of 2',4'-constrained 2'O-methoxyethyl and 2',4'-constrained 2'O-ethyl nucleic acid analogues. J Org Chem. 2010 Mar 5;75(5):1569-81.
• Shipping Conditions: Blue Ice
• Clinical Information: No Development Reported