Tazemetostat de(methyl morpholine)-COOH
CAT:
804-HY-147091-05
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Tazemetostat de(methyl morpholine)-COOH
- CAS Number: 2685873-44-1
- UNSPSC Description: Tazemetostat de(methyl morpholine)-COOH (compound 7) is a ligand for the PROTAC target protein EZH2, which can be used to synthesis of EZH2 degraders (PROTACs). EZH2 degraders have potent cell viability inhibition in diffuse large B-cell lymphoma (DLBCL) and other subtypes of lymphoma[1].
- Target Antigen: Ligands for Target Protein for PROTAC
- Type: Reference compound
- Related Pathways: PROTAC
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/tazemetostat-de-methyl-morpholine-cooh.html
- Solubility: DMSO : 220 mg/mL (ultrasonic)
- Smiles: O=C(C1=CC=C(C2=CC(C(NCC3=C(C)C=C(C)NC3=O)=O)=C(C)C(N(C4CCOCC4)CC)=C2)C=C1)O
- Molecular Weight: 517.62
- References & Citations: [1]Tu Y, Sun Y, et al. Design, Synthesis, and Evaluation of VHL-Based EZH2 Degraders to Enhance Therapeutic Activity against Lymphoma. J Med Chem. 2021 Jul 22;64(14):10167-10184.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported