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CAT: 0013-GTR19029291Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19029291Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This tripeptide functions as a substance P antagonist (IC50 = 90 μM) and inhibits its binding to MRGPRX2. It blocks SP-induced, IgE-independent mast cell degranulation in vitro and suppresses compound 48/80-evoked MRGPRX2 activation and scratching behavior in murine models in vivo, supporting neuroimmunology and pruritus research.
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Molecular Weight
697.78
Storage Conditions
-20°C
Notes
For research use only.

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