Recombinant Human/Mouse/Rat GDF-8/Myostatin

Recombinant Human/Mouse/Rat GDF-8/Myostatin

• Background: Growth/differentiation factor 8(Mstn, GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer, and interacts with WFIKKN2, leading to inhibit its activity. This protein can act specifically as a negative regulator of skeletal muscle growth. It regulates cell growth and differentiation in both embryonic and adult tissues.
• Abbreviation: GDF-8;Myostatin
• Synonyms: GDF-8, Gdf8, Growth/differentiation factor 8, Mstn, Myostatin
• CAS Number: 9000-83-3
• UniProt: O14793
• Accession Number: O14793
• Host: HEK293 Cells
• Origin Species: Human, Mouse, Rat
• Tag: None
• Sequence: Lys262-Ser375
• Field of Research: Signal Transduction;Cell biology;Neuroscience;Cancer;
• Purity: > 95 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 12-15 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.