Recombinant Rat UNC5B/UNC5H2 Protein (Fc Tag)

CAT:
763-PKSR030375
Size:
100 µg
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Recombinant Rat UNC5B/UNC5H2 Protein (Fc Tag) - image 1

Recombinant Rat UNC5B/UNC5H2 Protein (Fc Tag)

  • Background:

    The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium sulfate, or DSS-induced apoptosis and caspase-3 activity. In addition, is a potential anti-neoplastic target in bladder cancer progression and inflammatory arthritis.
  • Synonyms:

    UNC5B
  • UniProt:

    O08722
  • Accession Number:

    NP_071543.1
  • Expression System:

    HEK293 Cells
  • Tag:

    C-hFc
  • Sequence:

    Met1-Asp373
  • Endotoxin:

    < 1.0 EU per μg of the protein as determined by the LAL method.
  • Purity:

    > 85 % as determined by reducing SDS-PAGE.
  • Bioactivity:

    Not validated for activity
  • Reconstitution:

    Please refer to the printed manual for detailed information.
  • Shipping Conditions:

    This product is provided as lyophilized powder which is shipped with ice packs.
  • Storage Conditions:

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Calculated Molecular Weight:

    65.7 kDa
  • Observed Molecular Weight:

    72 - 90 kDa
  • Formulation:

    Lyophilized from sterile PBS, pH 7.4
    Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
    Please refer to the specific buffer information in the printed manual.
  • Species:

    Rat