Recombinant Macaca mulatta AHSG/Fetuin A Protein (His Tag)

• Background:

  Alpha-2-HS-glycoprotein (AHSG) is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the Cystatin family of proteases inhibitors. It is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. AHSG is an important circulating inhibitor of calcification in vivo, and is downregulated during the acute-phase response. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. In addition, AHSG may influence the resolution of inflammation by modulating the phagocytosis of apoptotic cells by macrophages. ASHG blocks TGF-beta-dependent signaling in osteoblastic cells.

• Abbreviation:

  Macaca mulatta AHSG; Fetuin A

• Synonyms:

  AHSG; Fetuin A; Macaca mulatta α-2-HS-Glycoprotein

• UniProt:

  F6WRS6

• Accession Number:

  A0A2K6AQI2

• Expression System:

  HEK293 Cells

• Tag:

  C-His

• Sequence:

  Ala19-Val367

• Endotoxin:

  < 1.0 EU per μg of the protein as determined by the LAL method.

• Purity:

  > 95 % as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  Please refer to the printed manual for detailed information.

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  38.9 kDa

• Observed Molecular Weight:

  45-70 kDa

• Species:

  Macaca mulatta