Recombinant Mouse IL-2 Receptor Subunit Beta/IL-2RB/CD122 (C-Fc)
CAT:
763-PKSM041435-02
Size:
50 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No


Recombinant Mouse IL-2 Receptor Subunit Beta/IL-2RB/CD122 (C-Fc)
Background:
IL-2RB, also known asinterleukin-2 receptor subunit beta, is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein, and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs.Abbreviation:
IL-2RB, CD122Synonyms:
CD122; High affinity IL-2 receptor subunit beta; IL15Rbeta; IL-15Rbeta; IL-2 receptor subunit beta; Il-2/15Rbeta; IL-2R subunit beta; IL-2RB; Il-2Rbeta; Interleukin-2 receptor subunit beta; p70; p70-75; Il2rb; IL-2R& beta; IL15RB; Interleukin-15 receptor subunit beta; p75UniProt:
P16297Accession Number:
P16297Expression System:
HEK293 CellsTag:
C-FcSequence:
Ala27-Glu240Endotoxin:
< 1.0 EU per μg of the protein as determined by the LAL method.Purity:
> 95 % as determined by reducing SDS-PAGE.Bioactivity:
Not validated for activityReconstitution:
Please refer to the printed manual for detailed information.Shipping Conditions:
This product is provided as lyophilized powder which is shipped with ice packs.Storage Conditions:
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.Calculated Molecular Weight:
52.2 kDaObserved Molecular Weight:
70 - 110 kDaFormulation:
Lyophilized from a 0.2 µm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.5.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.Species:
Mouse