Recombinant Mouse IL-2 Receptor Subunit Beta/IL-2RB/CD122 (C-Fc)

CAT:
763-PKSM041435-02
Size:
50 µg
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Recombinant Mouse IL-2 Receptor Subunit Beta/IL-2RB/CD122 (C-Fc) - image 1

Recombinant Mouse IL-2 Receptor Subunit Beta/IL-2RB/CD122 (C-Fc)

  • Background:

    IL-2RB, also known asinterleukin-2 receptor subunit beta, is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein, and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs.
  • Abbreviation:

    IL-2RB, CD122
  • Synonyms:

    CD122; High affinity IL-2 receptor subunit beta; IL15Rbeta; IL-15Rbeta; IL-2 receptor subunit beta; Il-2/15Rbeta; IL-2R subunit beta; IL-2RB; Il-2Rbeta; Interleukin-2 receptor subunit beta; p70; p70-75; Il2rb; IL-2R& beta; IL15RB; Interleukin-15 receptor subunit beta; p75
  • UniProt:

    P16297
  • Accession Number:

    P16297
  • Expression System:

    HEK293 Cells
  • Tag:

    C-Fc
  • Sequence:

    Ala27-Glu240
  • Endotoxin:

    < 1.0 EU per μg of the protein as determined by the LAL method.
  • Purity:

    > 95 % as determined by reducing SDS-PAGE.
  • Bioactivity:

    Not validated for activity
  • Reconstitution:

    Please refer to the printed manual for detailed information.
  • Shipping Conditions:

    This product is provided as lyophilized powder which is shipped with ice packs.
  • Storage Conditions:

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Calculated Molecular Weight:

    52.2 kDa
  • Observed Molecular Weight:

    70 - 110 kDa
  • Formulation:

    Lyophilized from a 0.2 µm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.5.
    Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
    Please refer to the specific buffer information in the printed manual.
  • Species:

    Mouse