Recombinant Mouse Serpin F1/PEDF Protein

• Background:

  Serpin F1 is secreted Neurotrophic protein and belongs to the serpin family. Serpin F1 Highly expressed in the liver, gastric glandular mucosa and renal tubules. It is also expressed in the brain, heart, lung retina and testes. It induces extensive neuronal differentiation in retinoblastoma cells. It is potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, exhibits no serine protease inhibitory activity.

• Abbreviation:

  Serpin F1; PEDF

• Synonyms:

  Caspin; Pedf; Pigment epithelium-derived factor; Sdf3; Serpin F1; Stromal cell-derived factor 3.

• Accession Number:

  P97298

• Expression System:

  E.coli

• Tag:

  None

• Sequence:

  Asp43-Thr417

• Endotoxin:

  < 1.0 EU per μg of the protein as determined by the LAL method.

• Purity:

  > 95 % as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  Not Applicable

• Shipping Conditions:

  This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

• Storage Conditions:

  Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

• Calculated Molecular Weight:

  42.0 kDa

• Observed Molecular Weight:

  40 kDa

• Formulation:

  Supplied as a 0.2 μm filtered solution of PBS, pH7.4.

• Species:

  Mouse