Recombinant Mouse ICAM-2/CD102 Protein (Fc Tag)

Recombinant Mouse ICAM-2/CD102 Protein (Fc Tag)

• Background: ICAM-2 is a 55-65 kD transmembrane glycoprotein possessing 2 extracellular Ig domains, a single transmembrane domain, and a short 26-amino acid cytoplasmic domain. ICAM-2 is expressed on most leukocytes, and is strongly expressed on vascular endothelial cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocytewith other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relation with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment.
• Abbreviation: ICAM-2;CD102
• Synonyms: CD102, CD102 antigen, ICAM-2, Icam-2, Icam2, Intercellular adhesion molecule 2, Ly-60, Lymphocyte function-associated AG-1 counter-receptor
• CAS Number: 9000-83-3
• Accession Number: P35330
• Host: HEK293 Cells
• Origin Species: Mouse
• Tag: C-Fc
• Sequence: Lys23-Gln222
• Purity: > 95 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 70-90 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.