Recombinant Human IL-1 Receptor Accessory Protein/IL-1RAcP/IL-1R3 (C-6His)
CAT:
763-PKSH034050-01
Size:
50 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Recombinant Human IL-1 Receptor Accessory Protein/IL-1RAcP/IL-1R3 (C-6His)
- Background: Interleukin-1 Receptor Accessory Protein (IL-1RAcP) is a member of the interleukin-1 receptor family. It contains three Ig-like C2-type domains in the extracellular region and a long cytoplasmic domain implicated in signal transduction. IL-1RAcP acts as a non-ligand binding accessory component of the receptors for IL1α, IL1βand IL33. IL-1RAcP mediates interleukin-1-dependent activation of NF-kappa-B. It is part of the membrane-bound form of the IL-1 receptor. IL-1 RAcP takes part in the Signaling ways by the formation of a ternary complex containing IL1R1, TOLLIP, MYD88, and IRAK1 or IRAK2. In addition, IL-1RAcP modulates the response to interleukins by associating with soluble IL1R1 and enhancing interleukin-binding to the decoy receptor.
- Abbreviation: IL-1RAcP;IL-1R3
- Synonyms: IL1R, Interleukin-1 Receptor, C3orf, IL-1 Receptor Accessory Protein, IL-1R3, IL-1R-3, IL-1RAcP, Interleukin-1 Receptor 3, Interleukin-1 Receptor Accessory Protein, C3orf13, IL1R3, IL1RAP, FLJ37788, IL 1 receptor accessory protein, IL 1R3, IL 1RAcP, IL 1RAP, Interleukin 1 Accessory Protein, interleukin 1 receptor 3, Interleukin 1 receptor accessory protein
- CAS Number: 9000-83-3
- UniProt: Q9NPH3
- Accession Number: Q9NPH3
- Host: HEK293 Cells
- Origin Species: Human
- Tag: C-His
- Sequence: Ser21-Glu359
- Field of Research: Cardiovascular;immunology
- Purity: > 95 % as determined by reducing SDS-PAGE.
- Bioactivity: Not validated for activity
- Reconstitution: Please refer to the printed manual for detailed information.
- Molecular Weight: 50-80 kDa
- Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
- Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.