Recombinant Human TNFRSF8/CD30L Receptor/CD30 (C-mFc)

Recombinant Human TNFRSF8/CD30L Receptor/CD30 (C-mFc)

• Background: CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody responses. CD30 is expressed by activated, but not by resting, T and B cells. Aberrant expression of CD30 by mastocytosis mast cells and interaction with its ligand CD30L (CD153) appears to play an important role in the pathogenesis and clinical presentation of systemic mastocytosis. CD30 has been considered as a specific diagnostic biomarker of anaplastic large cell lymphoma (ALCL) and classical Hodgkin lymphoma (cHL). CD30 is also a biomarker used for targeted therapy by an antibody–drug conjugate.
• Abbreviation: TNFRSF8;CD30L Receptor;CD30
• Synonyms: CD30, CD30L receptor, Ki-1 antigen, Lymphocyte activation antigen CD30, TNFRSF8, Tumor necrosis factor receptor superfamily member 8
• CAS Number: 9000-83-3
• UniProt: P28908
• Accession Number: P28908
• Host: HEK293 Cells
• Origin Species: Human
• Tag: C-mFc
• Sequence: Phe19-Lys379
• Field of Research: Cancer;immunology
• Purity: > 95 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 90-120 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.