Recombinant Human TNFRSF8/CD30L Receptor/CD30 (C-mFc) | Gentaur

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Recombinant Human TNFRSF8/CD30L Receptor/CD30 (C-mFc)

CAT:

763-PKSH034046-01

Size:

50 µg

Price:

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For price, please contact [email protected].

Recombinant Human TNFRSF8/CD30L Receptor/CD30 (C-mFc)

Background: CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody responses. CD30 is expressed by activated, but not by resting, T and B cells. Aberrant expression of CD30 by mastocytosis mast cells and interaction with its ligand CD30L (CD153) appears to play an important role in the pathogenesis and clinical presentation of systemic mastocytosis. CD30 has been considered as a specific diagnostic biomarker of anaplastic large cell lymphoma (ALCL) and classical Hodgkin lymphoma (cHL). CD30 is also a biomarker used for targeted therapy by an antibody–drug conjugate.
Abbreviation: TNFRSF8;CD30L Receptor;CD30
Synonyms: CD30, CD30L receptor, Ki-1 antigen, Lymphocyte activation antigen CD30, TNFRSF8, Tumor necrosis factor receptor superfamily member 8
UniProt: P28908
Accession Number: P28908
Host: HEK293 Cells
Origin Species: Human
Tag: C-mFc
Sequence: Phe19-Lys379
Field of Research: Cancer;immunology
Purity: > 95 % as determined by reducing SDS-PAGE.
Bioactivity: Not validated for activity
Reconstitution: Please refer to the printed manual for detailed information.
Molecular Weight: 90-120 kDa
Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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