Recombinant Human CD30/TNFRSF8 Protein (His Tag) | Gentaur

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Recombinant Human CD30/TNFRSF8 Protein (His Tag)

CAT:

763-PKSH031431

Size:

100 µg

Price:

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For price, please contact [email protected].

Recombinant Human CD30/TNFRSF8 Protein (His Tag)

Background: CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of lymphocytes and may also play an important role in human immunodeficiency virus replication. As a regulator of apoptosis, CD30 protein induces cell death or proliferation, depending on the cell type, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. CD30 protein expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs), and CD30 is also linked to leukocytes in patients with chronic inflammatory diseases, including lupus erythematosus, asthma, rheumatoid arthritis and atopic dermatitis (AD).
Synonyms: CD30, CD30L receptor, D1S166E, Ki-1 antigen, Lymphocyte activation antigen CD30, TNFRSF8, Tumor necrosis factor receptor superfamily member 8
Accession Number: NP_001234.2
Host: HEK293 Cells
Origin Species: Human
Tag: C-His
Sequence: Met 1-Lys 379
Applications: ELISA
Purity: > 95 % as determined by reducing SDS-PAGE.
Bioactivity: Measured by its binding ability in a functional ELISA. 2. Immobilized recombinant human CD30 at 2 μg/ml (100 μl/well) can bind human CD30L Fc Chimera with a linear range of 6. 4-800 ng/ml.
Reconstitution: Please refer to the printed manual for detailed information.
Molecular Weight: 75-90 kDa
Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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