Recombinant Human Angiopoietin-1/ANG1 (N-Fc)
CAT:
763-PKSH033955-01
Size:
50 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Recombinant Human Angiopoietin-1/ANG1 (N-Fc)
- Background: Angiopoietin-1 (Ang-1) is a secreted glycoprotein that plays a critical role in the development and maintenance of the vascular system. The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. Angiopoietin-1 can protect against pulmonary arterial hypertension, reduce the extent of fibrosis and remodeling in infarcted diabetic myocardium, and enhance tumor progression and metastasis.
- Abbreviation: Angiopoietin-1;ANG1
- Synonyms: AGP1, AGPT, ANG-1, ANGPT1, Ang1, Angiopoietin-1, angiopoietin 1
- CAS Number: 9000-83-3
- UniProt: Q15389
- Accession Number: Q15389
- Host: HEK293 Cells
- Origin Species: Human
- Tag: N-Fc
- Sequence: Asp256-Phe498
- Field of Research: Cardiovascular;Cancer;metabolism
- Purity: > 95 % as determined by reducing SDS-PAGE.
- Bioactivity: Not validated for activity
- Reconstitution: Please refer to the printed manual for detailed information.
- Molecular Weight: 55-65 kDa
- Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
- Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.