Recombinant Human Interleukin-13/IL-13 (C-Fc)

Recombinant Human Interleukin-13/IL-13 (C-Fc)

• Background: Interleukin-13 is also known as IL-13. It is a protein that in humans is encoded by the IL13 gene. Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils.
• Abbreviation: Interleukin-13;IL-13
• Synonyms: BHR, Interleukin, T-Cell Activation Protein P, ALRH, BHR1, T-Cell Activation Protein P600, Interleukin-13, IL13, NC30, P600, Il-13
• CAS Number: 9000-83-3
• UniProt: P35225
• Accession Number: AAK53823
• Host: HEK293 Cells
• Origin Species: Human
• Tag: C-Fc
• Sequence: Gly21 Asn132
• Field of Research: Immunology,Cancer,Kits,Lysates,Other,Cardiovascular
• Purity: > 95 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 39-60 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.