Recombinant Human DPP4/DPPIV/CD26 Protein (His Tag)

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Recombinant Human DPP4/DPPIV/CD26 Protein (His Tag)

CAT:

763-PKSH033695-02

Size:

10 µg

Price:

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For price, please contact [email protected].

Recombinant Human DPP4/DPPIV/CD26 Protein (His Tag)

Background: CD26 is a signal-anchor for type II membrane protein that belongs to the peptidase S9B family. CD26 is expressed specifically in lymphatic vessels but not in blood vessels in the skin; small intestine; esophagus; ovary; breast and prostate glands. It acts as a positive regulator of T-cell coactivation; by binding at least ADA; CAV1; IGF2R; and PTPRC. It’s binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM); the migration and invasion of endothelial cells into the ECM. It may be involved in the promotion of lymphatic endothelial cells adhesion; migration and tube formation. When overexpressed; it enhanced cell proliferation; a process inhibited by GPC3. It acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation; including many chemokines; mitogenic growth factors; neuropeptides and peptide hormones.
Abbreviation: DPP4;DPPIV;CD26
Synonyms: ADABP, ADCP-2, Adenosine deaminase complexing protein 2, DPP IV, Dipeptidyl peptidase 4, Dipeptidyl peptidase IV, T-cell activation antigen CD26
UniProt: P27487
Accession Number: P27487
Host: HEK293 Cells
Origin Species: Human
Tag: C-His
Sequence: Asn29-Pro766
Field of Research: Cell biology;Cancer;immunology;metabolism;Stem cells
Purity: > 95 % as determined by reducing SDS-PAGE.
Bioactivity: Not validated for activity
Reconstitution: Please refer to the printed manual for detailed information.
Molecular Weight: 90-130 kDa
Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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Cat	Name
PKSH033695-02	Recombinant Human DPP4/DPPIV/CD26 Protein (His Tag)
PKSH030456	Recombinant Human DPP4/DPPIV/CD26 Protein (Fc Tag)
PKSH033696-01	Recombinant Human DPP4/DPPIV/CD26 Protein (Fc Tag)
PKSH033696-02	Recombinant Human DPP4/DPPIV/CD26 Protein (Fc Tag)
PKSH033695-01	Recombinant Human DPP4/DPPIV/CD26 Protein (His Tag)
PKSH033811	Recombinant Human DPP4/CD26 Protein
AN006030L-02	DPP4/CD26 Polyclonal antibody
AN006840L-01	DPP4/CD26 Polyclonal Antibody
AN006030L-01	DPP4/CD26 Polyclonal antibody
AN006840L-02	DPP4/CD26 Polyclonal Antibody