Recombinant Human VEGF-B/VEGFB Protein (Fc Tag)

Recombinant Human VEGF-B/VEGFB Protein (Fc Tag)

• Background: VEGFB, as known as VRF, is a member of the VEGF family of growth factors that share structural and functional similarity. By alternative splicing, two isoforms of mature VEGF-B containing 167 or 186 amino acid (aa) residues exist. VEGF-B is expressed in most tissues, especially in heart, skeletal muscle and pancreas. The two VEGF-B isoforms have identical amino-terminal cysteine-knot VEGF homology domains but the carboxyl end of VEGF-B167 differs from that of VEGF-B186 by the presence of a highly basic cysteine-rich heparin binding domain. VEGF-B167 and a proteolytically processed form of VEGF-B186 also bind neuropilin-1, a type I transmembrane receptor for semaphorins/collapsins, ligands involved in neuron guidance.
• Abbreviation: VEGF-B;VEGFB
• Synonyms: VEGF-B, VEGF-related factor, VRF, Vascular endothelial growth factor B
• CAS Number: 9000-83-3
• UniProt: P49765
• Accession Number: P49765
• Host: HEK293 Cells
• Origin Species: Human
• Tag: N-Fc
• Sequence: Pro22-Ala207
• Field of Research: Signal Transduction;Cardiovascular;Neuroscience;Cancer;
• Purity: > 95 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 40&60 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.