Recombinant Human LMIR2/CD300C Protein (Fc Tag)

• Background:

  CD300C is a single-pass type I membrane protein which belongs to the immunoregulatory signaling (IRS) family. CD300C contains one Ig-like V-type domain and is present on the surface of natural killer cells; granulocytes; most myeloid cells; dendritic cells; and a subpopulation of T and B lymphocytes. The CD300C (CMRF-35A) and CD300A (CMRF-35H) molecules are homologous leukocyte surface proteins. CD300a and CD300C play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from pDCs. CD300A and CD300C are indistinguishable on the surface of NK cells. The ligand for CD300C is presently unknown.

• Abbreviation:

  LMIR2; CD300C

• Synonyms:

  CD300 Antigen-Like Family Member C; CD300C; CD300c; CLM-6; CMRF-35; CMRF35; CMRF35-A1; CMRF35-Like Molecule 6; CMRF35A; CMRF35A1; IGSF16; IgSF16; Immunoglobulin Superfamily Member 16

• UniProt:

  Q08708

• Accession Number:

  Q08708

• Expression System:

  HEK293 Cells

• Tag:

  C-Fc

• Sequence:

  Gly21-Arg183

• Field of Research:

  Immunology

• Endotoxin:

  < 1.0 EU per μg of the protein as determined by the LAL method.

• Purity:

  > 90 % as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  Please refer to the printed manual for detailed information.

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  44.9 kDa

• Observed Molecular Weight:

  60-90 kDa

• Species:

  Human