Recombinant Human Interleukin-17F/IL-17F Protein

Recombinant Human Interleukin-17F/IL-17F Protein

• Background: Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today; IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family; IL-17A through IL-17F; are secreted as homodimers. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis.
• Abbreviation: Interleukin-17F;IL-17F
• Synonyms: Cytokine ML, Interleukin, CANDF, IL17F, CANDF6, IL-17F, ML-1, ML1, Cytokine ML-1, IL24, IL-24, Interleukin-17F, Interleukin-24
• CAS Number: 9000-83-3
• UniProt: Q96PD4
• Accession Number: Q96PD4
• Host: E. coli
• Origin Species: Human
• Tag: C-His
• Sequence: Arg31-Gln163
• Applications: Cell culture
• Field of Research: Cardiovascular;Cancer;immunology
• Purity: > 98 % as determined by reducing SDS-PAGE.
• Bioactivity: Measure by its ability to induce IL-6 secretion in 3T3 cells. The ED₅₀ for this effect is <20 ng/mL.
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 18 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.