Recombinant Human Interferon γ/IFNG Protein
CAT:
763-PKSH032612-02
Size:
20 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Recombinant Human Interferon γ/IFNG Protein
- Background: IFNγ is the major interferon produced by mitogenically or antigenically stimulated lymphocytes. It is structurally different from type I interferon and its major activity is immunoregulation. It has been implicated in the expression of class II histocompatibility antigens in cells that do not normally produce them; leading to autoimmune disease. Interferon gamma is produced mainly byT-cells and natural killer cells activated by antigens; mitogens; or alloantigens. It is produced by lymphocytes expressing the surface antigens CD4 and CD8. IFNγ synthesis is induced by IL-2; FGF-basic; and EGF.
- Abbreviation: Interferon γ;IFNG
- Synonyms: IFN-Gamma, IFNG, Immune Interferon, Interferon Gamma
- CAS Number: 9000-83-3
- UniProt: P01579
- Accession Number: P01579
- Host: E. coli
- Origin Species: Human
- Tag: C-His
- Sequence: Gln24-Gln166
- Applications: Cell culture
- Field of Research: Cancer;immunology;Stem cells
- Purity: > 95 % as determined by reducing SDS-PAGE.
- Bioactivity: Measure by its ability to induce cytotoxicity in HT29 cells. The ED50 for this effect is <1 ng/mL. The specific activity of recombinant human IFN gamma is approximately >2 x 106 IU/mg.
- Reconstitution: Please refer to the printed manual for detailed information.
- Molecular Weight: 17 kDa
- Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
- Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.