Recombinant Human GRB2 Protein (His Tag) | Gentaur

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Recombinant Human GRB2 Protein (His Tag)

CAT:

763-PKSH032512-01

Size:

50 µg

Price:

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For price, please contact [email protected].

Recombinant Human GRB2 Protein (His Tag)

Background: As an adaptor protein, Growth Factor Receptor-Bound Protein 2 (GRB2) is involved in siganl transduction and consists of a central SH2 domain flanked by two SH3 domains. GRB2 associates with activated Tyr-phosphorylated EGF receptor/EGFR and PDGF receptors via its SH2 domain, stimulating GTP binding to Ras, which in turn activates MAPK and other signaling pathway.It also associates to other cellular Tyr-phosphorylated proteins such as SIT1, IRS1, IRS4, SHC and LNK. probably via the concerted action of both its SH2 and SH3 domains.
Abbreviation: GRB2
Synonyms: ASH, Adapter Protein GRB2, GRB2, Growth Factor Receptor-Bound Protein 2, Protein Ash, SH2/SH3 Adapter GRB2
UniProt: P62993
Accession Number: P62993
Host: E. coli
Origin Species: Human
Tag: C-His
Sequence: Met 1-Val217
Field of Research: Signal Transduction;Cancer;
Purity: > 90 % as determined by reducing SDS-PAGE.
Bioactivity: Not validated for activity
Reconstitution: Please refer to the printed manual for detailed information.
Molecular Weight: 25-30 kDa
Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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PKSH032512-02	Recombinant Human GRB2 Protein (His Tag)
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