Recombinant Human EIF4EBP2 Protein (His Tag)

• Background:

  Eukaryotic Translation Initiation Factor 4E-Binding Protein 2 (EIF4EBP2) is a member of the Eukaryotic Translation Initiation Factor 4E Binding Protein Family. EIF4EBP2 regulates eIF4E activity by preventing its assembly into the eIF4F complex, mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase pathway. This regulation of is associated to cell proliferation, cell differentiation and viral infection. Phosphorylated EIF4EBP2 on serine and threonine residues in response to insulin, EGF and PDGF.

• Abbreviation:

  EIF4EBP2

• Synonyms:

  4E-BP2; EIF4EBP2; Eukaryotic Translation Initiation Factor 4E-Binding Protein 2; eIF4E-Binding Protein 2

• UniProt:

  Q13542

• Accession Number:

  Q13542

• Expression System:

  E.coli

• Tag:

  N-His

• Sequence:

  Met 1-Ile120

• Field of Research:

  Epigenetics and nuclear signal; metabolism

• Endotoxin:

  < 1.0 EU per μg of the protein as determined by the LAL method.

• Purity:

  > 90 % as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  Please refer to the printed manual for detailed information.

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  15.1 kDa

• Observed Molecular Weight:

  19&20 kDa

• Species:

  Human