Recombinant Human CFHR2 Protein (His Tag)

• Background:

  Complement Factor H-Related Protein 2 (CFHR2) is a secreted protein that belongs to the complement factor H protein family. Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. CFHR2 is synthesized as a 270 amino acid precursor that contains an 18 amino acid signal peptide and a 252 amino acid mature chain with 4 Sushi (CCP/SCR) domains. CFHR2 is synthesized in the liver and secreted into plasma. It may be involved in complement regulation. CFHR2 can also be associated with lipoproteins and may play a role in lipid metabolism.

• Abbreviation:

  CFHR2

• Synonyms:

  CFHL2; CFHR2; Complement Factor H-Related Protein 2; DDESK59; FHR-2; FHR2; H Factor-Like 3; H Factor-Like Protein 2; HFL3

• UniProt:

  P36980

• Accession Number:

  P36980

• Expression System:

  HEK293 Cells

• Tag:

  C-His

• Sequence:

  Glu19-Lys270

• Field of Research:

  Signal Transduction; Cancer; immunology; metabolism

• Endotoxin:

  < 1.0 EU per μg of the protein as determined by the LAL method.

• Purity:

  > 95 % as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  Please refer to the printed manual for detailed information.

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  29.8 kDa

• Observed Molecular Weight:

  31&35 kDa

• Species:

  Human