Recombinant Human CCL5/RANTES Protein

Recombinant Human CCL5/RANTES Protein

• Background: Human Chemokine (C-C Motif) Ligand 5 (CCL5) plays an active role in recruiting leukocytes into inflammatory sites. CCL5 is secreted by many cell types at inflammatory sites and it exerts a wide range of activities through the receptors CCR1, CCR3, CCR4, and CCR5. N-Terminal truncated CCL5/RANTES, Met-RANTES, and amino-oxypentane (AOP)-RANTES exhibit antagonist or partial agonist functions on their receptors. CCL5/RANTES attracts different subtypes of leukocytes into inflamed tissue and intervenes in a wide range of allergic and autoimmune diseases.
• Abbreviation: CCL5;RANTES
• Synonyms: C-C Motif Chemokine 5, CCL5, D17S136E, EoCP, Eosinophil Chemotactic Cytokine, SCYA5, SIS-Delta, Small-Inducible Cytokine A5, T Cell-Specific Protein P228, T-Cell-Specific Protein RANTES, TCP228
• CAS Number: 9000-83-3
• UniProt: P13501
• Accession Number: P13501
• Host: E. coli
• Origin Species: Human
• Tag: None
• Sequence: Ser24-Ser91
• Field of Research: Cardiovascular;immunology
• Purity: > 95 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 9-12 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.