Recombinant Human Apolipoprotein C-II/APOC2 Protein (His Tag)

Recombinant Human Apolipoprotein C-II/APOC2 Protein (His Tag)

• Background: APOC2 activates the lipoprotein lipase in capillaries, which hydrolyzes triglycerides and thus provides free fatty acids for cells. APOC2 is component of the very low density lipoprotein (VLDL) fraction in plasma. It is also an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoproteinemia type 1B (HLPP1B) which characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis.
• Abbreviation: Apolipoprotein C-II;APOC2
• Synonyms: APC2 and APOC2, Apolipoprotein C-II, Apolipoprotein C2
• CAS Number: 9000-83-3
• UniProt: P02655
• Accession Number: AAP35354.1
• Host: E. coli
• Origin Species: Human
• Tag: C-His
• Sequence: Thr23-Glu101
• Field of Research: Signal Transduction;Cardiovascular;Cancer;metabolism;
• Purity: > 95 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Not Applicable
• Molecular Weight: 14 kDa
• Shipping Conditions: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
• Storage Conditions: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.