Recombinant Human CD3D & CD3E Heterodimer Protein

Recombinant Human CD3D & CD3E Heterodimer Protein

• Background: T-cell surface glycoprotein CD3D & CD3E, also known as CD3 delta & CD3 epsilon chain, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
• Synonyms: CD3D, CD3d, T-Cell Receptor T3 Delta Chain, T-Cell Surface Glycoprotein CD3 Delta Chain, T3D
• CAS Number: 9000-83-3
• UniProt: P04234;P07766
• Accession Number: P04234-1&P07766-1
• Host: HEK293 Cells
• Origin Species: Human
• Tag: C-Flag-hFc
• Sequence: Met 1-Ala105&Met 1-Asp126
• Applications: ELISA
• Field of Research: immunology;Stem cells
• Purity: > 90 % as determined by reducing SDS-PAGE.
• Bioactivity: Measured by its binding ability in a functional ELISA. Immobilized human CD3D & CD3E Heterodimer Protein at 10 μg/ml (100 μl/well) can bind OKT3-mIgG2a. The EC50 of OKT3-mIgG2a is 0.07-0.17 μg/ml.
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 45-50 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.