LT-beta Polyclonal Antibody

CAT: 0965-JOT-AP10992-01Size: 20 µLDry Ice: NoHazardous: No

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CAT#:0965-JOT-AP10992-01Size:20 µL

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Background

Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.

CAS Number

9007-83-4

Synonyms

Lymphotoxin-beta; LTB; TNFC; TNFSF3; Lymphotoxin-beta; LT-beta; Tumor necrosis factor C; TNF-C; Tumor necrosis factor ligand superfamily member 3

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human TNFC. AA range:181-230

Clonality

Polyclonal

Applications

WB, IF, ICC, ELISA

Stability

-20°C for 1 year

Concentration

1 mg/ml

Molecular Weight

25390

Antibody Type

Primary antibody

Isotype

IgG

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LT-beta Polyclonal Antibody

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