BMP2 Monoclonal Antibody

• Background:

  Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer, which binds to its receptor. There is also a 40-45 kDa form of BMP2, as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction.

• Abbreviation:

  BMP2

• UniProt:

  P12643, P21274, P49001

• Host:

  Mouse

• Reactivity:

  Rat

• Immunogen:

  Recombinant protein corresponding to Mouse BMP2

• Target:

  BDA2; BMP-2; BMP-2A; Bmp2; BMP2; BMP2A; Bone morphogenetic protein 2; Bone morphogenetic protein 2A

• Clonality:

  Monoclonal

• Clone:

  2H6D12

• Conjugation:

  Unconjugated

• Applications:

  IHC

• Field of Research:

  Cancer; Cardiovascular; Signal Transduction; Stem Cells

• Purification:

  Affinity purification

• Concentration:

  2.65 mg/mL

• Dilution:

  IHC 1:200-1:800

• Buffer:

  PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG