BMP2 Polyclonal Antibody

• Background:

  Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer, which binds to its receptor. There is also a 40-45 kDa form of BMP2, as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction.

• Abbreviation:

  BMP2

• UniProt:

  P12643

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Synthetic peptide of human BMP2

• Target:

  BDA2; BMP-2; BMP-2A; Bmp2; BMP2; BMP2A; Bone morphogenetic protein 2; Bone morphogenetic protein 2A

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Cancer; Cardiovascular; Signal Transduction; Stem Cells

• Purification:

  Antigen affinity purification

• Concentration:

  1.4 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  45 kDa

• Observed Molecular Weight:

  Refer to figures

• Isotype:

  IgG