C-Kit Polyclonal Antibody

• Background :

  This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor) . Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

• Abbreviation :

  C-Kit

• UniProt :

  P10721, P05532

• Host :

  Rabbit

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Recombinant protein corresponding to Mouse c-Kit

• Target :

  C Kit; c-Kit; c-Kit Ligand; CD117; Kit; Kit Ligand; KIT oncogene; KIT proto oncogene receptor tyrosine kinase; KIT; Mast cell growth factor receptor; Mast/stem cell growth factor receptor Kit; MGF; p145 c-kit; PBT; Piebald trait protein; Proto oncogene c Kit; Proto oncogene tyrosine protein kinase Kit; Proto-oncogene c-Kit; SCF Receptor; SCFR; soluble KIT variant 1; Steel Factor Receptor; Stem cell factor receptor; tyrosine protein kinase Kit; Tyrosine-protein kinase Kit; v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog; v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB

• Field of Research :

  Cancer; Developmental Biology; Immunology; Neuroscience; Signal Transduction; Stem Cells; Tags and Cell Markers

• Purification :

  Affinity purification

• Concentration :

  3 mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  110kDa

• Observed Molecular Weight :

  145kDa

• Citation 01 :

  https://www.frontiersin.org/articles/10.3389/fphys.2022.828578/full?utm_source=dlvr.it&utm_medium=twitter

• Citation 02 :

  https://www.sciencedirect.com/science/article/pii/S0378874121001513

• Isotype :

  IgG