OCLN Polyclonal Antibody

• Background :

  Occludin is an integral membrane protein located at the tight junction. It is a tetraspanin protein with four transmembrane domains, intracellular N and C termini and two extracellular loops. Occludin plays a role in the formation and regulation of the tight junction paracellular permeability barrier. Occludin can exist in different isoforms, owing to modifications at the posttranscriptional and posttranslational levels .

• Abbreviation :

  OCLN

• UniProt :

  Q61146, Q6P6T5

• Host :

  Rabbit

• Reactivity :

  Mouse

• Immunogen :

  Recombinant protein corresponding to Mouse occludin

• Target :

  BLCPMG; FLJ08163; FLJ18079; FLJ77961; FLJ94056; MGC34277; Occludin; Ocln; OCLN; Phosphatase 1 regulatory subunit 115; PPP1R115; PTORCH1; Tight junction protein occludin

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB

• Field of Research :

  Cancer; Signal Transduction

• Purification :

  Affinity purification

• Concentration :

  0.56 mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  59kDa

• Observed Molecular Weight :

  60kDa

• Citation 01 :

  https://link.springer.com/article/10.1007/s00213-020-05605-w

• Citation 02 :

  https://www.sciencedirect.com/science/article/pii/S1382668920300880

• Isotype :

  IgG