NOX4 Polyclonal Antibody

• Background:

  This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS) . The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.

• Abbreviation:

  NOX4

• UniProt:

  Q9NPH5, Q9JHI8, Q924V1

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  KLH conjugated Synthetic peptide corresponding to Mouse NOX4

• Target:

  Kidney oxidase 1; Kidney oxidase-1; Kidney superoxide producing NADPH oxidase; Kidney superoxide-producing NADPH oxidase; KOX 1; KOX; Kox-1; KOX1; NADPH; NADPH oxidase 4; Nox4; NOX4; Renal NAD (P) H oxidase; Renal NAD (P) H-oxidase; RENOX

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Cancer; Cell Biology; Cardiovascular; Metabolism; Signal Transduction

• Purification:

  Affinity purification

• Concentration:

  0.9 mg/mL

• Dilution:

  WB 1:1000-1:2000; IHC 1:400-1:1000

• Buffer:

  PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  70kDa

• Observed Molecular Weight:

  70kDa

• Isotype:

  IgG